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I
W P C P S® 1
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Exhibitors
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Abstracts
Physical Characterization of
Molecular and Supramolecular
Organized Systems
Franck Leveiller
(Aventis Pharmaceuticals, France)
Solid State Development of a NNRTI
Drug Substance Candidate
Pascal H. Toma (DuPont, USA)
Exploring Polymorph Space: Making and
Analysing Solid Forms
Terry Threlfall (University of York, UK)
Polymorphism: Identification and Quantification
by XRD
Harvey Lieberman
(Aventis Pharmaceuticals, USA)
Unique
Applications of XRD, DSC, TG, NMR and Molecular Modeling in Pharmaceutical
Product Development
Marek Zakrzewski (Advanced Solid State Characterization
Inc., USA)
Qualitative and Quantitative Applications of Non-Ambient XRD
Raj Suryanarayanan (University of Minnesota, USA)
Characterizing the Effects of Processing on Pharmaceutical Solids
Michiel Van Oort (Glaxo Wellcome, USA)
Influence of Particle Properties on Processing
C. Randall (Sanofi-Synthélabo, USA)
Thermoanalytical Techniques for the Characterization of Drugs
and Dosage Forms
Raj Suryanarayanan (U. Minnesota, USA)
Pharmaceutical Applications of
Thermal Analysis -
Application of Modulated DSC to the Freeze Drying Process
Roger L. Blaine (TA Instruments, Inc., USA)
Structure and Properties, Prediction
and Determination:
Modelling of the Organic Solid State
Stephen J. Maginn (Cambridge Crystallographic Data
Centre, UK)
From Molecules to Crystals … and Back Again
Mike Zaworotko (U. South Florida, USA)
From Powders to Polymorphs : Structure
Solution by Global Rietveld Analysis
Kenneth Shankland (Rutherford Appleton Laboratory,
UK)
Solid Processing and Flowability Related with Physical Characterizations
Evelyne Chassagneux (Rhone Poulenc, France)
Surface
Characterisation of Pharmaceutical Materials
Using Inverse Gas Chromatography
Daryl R. Williams (Surface Measurement Systems
Limited, UK)
Sorption of Water by Solids
Cynthia A. Oksanen (Pfizer Inc, USA)
Use of Desiccants and Packaging
to Control
the Effects of Moisture on Solid Properties
Anthony Hlinak, Mark J. Kontny (Searle/Pharmacia,
USA)
Strategies for Patenting Pharmaceuticals
John Palmer (Ladas & Parry, USA)
Vibrational Spectroscopy - Does It Still Have A Role Now
That We All Have Powder Diffraction Capability?
Robert Lancaster (GlaxoWellcome, UK)
Polarized Light Microscopy - Can You Work Without It?
Gary Nichols (Pfizer, England)
FT-IR and Raman Microscopy of Single Crystals from X-Ray Diffraction
Studies
Gary E. Zuber, Lee Katrincic, James Rydzak, R.
Curtis Haltiwanger
and Drake S. Eggleston (SmithKline Beecham, USA)
Surveys of Polymorphic Transformations
Induced
by Variations in Temperature and Humidity
Norman Shankland (CrystallografX Limited, UK)
The Physical and Chemical Characterization
of the Solid State Forms of RWJ-38063
Daniel Korey*, Ahmed F. Abdel-Magid, Robert Partak,
Barry Fegely, Richard Kelly and Thomas Schultz (The Robert Wood
Johnson Pharmaceutical Research Institute, USA)
An Easy and Fast Approach for Precise
XRD Evaluation of Pharmaceuticals
Marek Zakrzewski (Advanced Solid State Characterization
Inc., USA),
Vladimir Kogan (Philips Analytical X-ray, Netherlands)
S. Prugovecki (Philips Analytical X-ray, Netherlands)
Percentage Crystallinity Determination
and Polycapillary X-Ray Optics
Simon Bates (Kratos Analytical, USA)
Investigation of the Effects of Temperature,
Relative Humidity and Milling on
Solid-State Decomposition of Aminophylline Using X-Ray Powder
Diffractometry
Suneel Rastogi (University of Minnesota, USA)
Marek Zakrzewski (Advanced Solid State Characterization Inc.,
USA)
Raj Suryanarayanan (Forest Laboratories, Inc., USA )
Small- and Wide-Angle X-Ray Scattering for the
Physical Characterization of Pharmaceutical Solids
P. Laggner (Austrian Academy of Sciences and Hecus
M. Braun X-Ray Systems, Austria)
Ultrasonic Attenuation Spectroscopy
for Particle Sizing in Industrial Crystallization
P. Mougin, K. Roberts, D. Wilkinson (Heriot-Watt
University, UK)
ATR FTIR Spectroscopy for On-Line Supersaturation
Control During Crystallisation of Pharmaceutically Important Substances
H. Groen and K. J. Roberts (Heriot-Watt University,
UK)
Chemical Imaging Of Pharmaceuticals
By TOF-SIMS
A.M. Belu (Physical Electronics, U.S.A)
M.C. Davies (University of Nottingham, U.K.)
J.M. Newton (University of London, U.K.)
N. Patel4 (Molecular Profiles Ltd., U.K.)
Synthesis, Nuclear Magnetic Resonance
and Thermal Analysis of Sodium and Platinum Complexes of Anticancer
6-Mercaptopurine
J. Bariyanga* and A.S. Luyt (University of the
North, So. Africa)
Measurement of Weak Glass Transitions in Amorphous Pharmaceutical
Formulations
M. Galop, (SmithKline Beecham, USA)
G.L. Collins, (TherMold, USA)
E.Y. Shalaev, (Pfizer Central Research, USA)
M.J. Pikal, (U. Connecticut, USA)
V. Radhakrishnan, (U. Connecticut, USA)
Validation of DSC and TGA for Pharmaceutical
Analysis
Under Current Good Manufacturing Practices
Robert P. Weissburg*, Fred E. Burris, Theodora
K. Ferrell, Eda Ross-Montgomery (DuPont Pharmaceuticals Company,
USA)
Low Temperature Infrared Spectroscopy of Hydrogen Bonding in Carbohydrates
- Tetritols, Pentitols and Pyranosides
Mark Rozenberg (Hebrew University of Jerusalem,
Israel)
Applications of Pressure Differential
Scanning Calorimetry
in the Study of Pharmaceutical Hydrates
Jun Han (Wyeth-Ayerst Research, USA)
Modelling in the Design of Habit Modifiers
Michael J. Quayle (University of Manchester, U.K.)
Whats in a Powder Diffraction Pattern?
William I. F. David (ISIS Facility, UK)
A Solid State Raman Spectrocopic Study
of the
Vibrations of Benzamide and Its Metastable
Form M. Song and R. J. Davey (University of Manchester,
UK)
Examination of the Impact of Moisture on Process
Induced Disorder in Pharmaceutical Solids
James J. Conners (Dura Pharmaceuticals, USA)
The Dynamics of Carbohydrate Surfaces: Effects of Water Sorption
Frank M. Etzler (Boehringer Ingelheim Pharmaceuticals
Inc., USA)
Ronald D. Neuman, & Tonia Burke (Auburn University, USA)
Influence of Sorbed Moisture on Processing Solid Dosage Forms
Anthony Hlinak, Margaret Vaughn (Pharmacia/Searle,
USA)
Structure Determination from Powder
and Single
Crystal Data by Simulated Annealing
A. Kern (Bruker-AXS GmbH, Germany)
Development Of An X-Ray Powder Diffraction (XRPD) Method For The
Quantitation Of Hydrate In A Drug Substance Solvate
Susan A. Lerke, Moisey Gamarnik and Paul K. Hovsepian
(DuPont Pharmaceuticals, USA)
CRIT Analytical Services in Physical Characterizations
Evelyne Chassagneux (CRIT - Rhone-Poulenc, France)
A New Fast and Automated Diffraction System for Combinatorial
Screening
P.J. LaPuma, J. Anzelmo, U. Preckwinkle,
B. Litteer, B. Nechkash Herrington (Bruker, USA)
Scale-up Studies on Batch Cooling Crystallization
of
Pharmaceutically Organic Substances
Liang K. J.; Willikinson D.; White, G.; Roberts,
K.J. (Heriot-Watt University, UK)
Temperature Controlled Humidity Chamber for X-Ray Diffraction
Analysis
Beckers, D. (Philips Analytical, The Netherlands)
Developing a Structurally Based Model
for Nucleation:
From Molecular Aggregation to Product Control
H.G. Alison, R.J. Davey, J. Garside, M.J. Quayle,
G.J.T. Tiddy,
(University of Manchester Institute of Science and Technology,
UK)
G.R. Jones, (CCLRC Daresbury Laboratory, UK)
The Surprising Compounds: Sulphathiazole, Sulphapyridine, Sulphanilamide
Ann Egan, David Hughes, Mike Hursthouse, Anne de
Paepe (Southampton University, UK) Robin Harris, Ian King, Alessia
Portieri (Durham University, UK)
Bob Lancaster (GlaxoWellcome, UK),
Gary Nichols (Pfizer, UK)
Stewart Tavener, Terry Threlfall (University of York, UK)
Structural Systematics: Turning Molecular
Structures Into Crystal Structures
Mike Hursthouse, Suzanna Ward, Tom Mayer (Southampton
University, UK) Bob Lancaster (GlaxoWellcome, UK)
Terry Threlfall (University of York, UK)
Investigation of the Adhesion Phenomena
of GW1000
and Lactose under Different Environmental Conditions
V. Carli, A. Dupont, F. Slimani, C. Laroche* (GlaxoWellcome,
UK)
The Advantages of Polycapillary Parallel-Beam
X-Ray
Optics for the Study of Pharmaceutical Samples
Haller, M. (X-ray Optical Systems, Inc., USA) Bates,
S. (Kratos Analytical, Inc., USA)
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