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S
h o r t C o u r s e s
On June 15, 2003 from 2PM to 6 PM
we are offering short courses on:
| I.
Microscopy: Seeing
is Believing |
Chairperson:
Gary
Nichols, Pfizer Global Research
and Development, UK
|
II.
Small and Wide Angle X-Ray Scattering:
Novel Approaches to the Nano-characterization
of Pharmaceutical Solids |
|
Chairperson:
Prof.
Dr. Peter Laggner, Austrian
Academy of Science, Austria
1.
Session:
Essential principals and techniques
2. Session:
Application examples from pharmaceutical materials
3. Session:
Test-drive with original dataset discussion, participant
suggestions and interest
|
| III.
X-ray Diffraction: X-Ray
Optics and Instrumentation |
|
Chairperson:
Dr.
Angeline Zakrzewski, assainternational®,
USA
1.
Essential basics of X-ray Diffraction.
Basic
crystallography, diffraction by crystals, x-ray powder
pattern
2.
Different setups
reflection,
transmission, capillary, monochromators, beta filters,
fixed and automatic slits, soller slits, parallel beam
optics, capillary lenses, x-ray mirrors, detectors: scintillation,
solids state and PSD
3.
Examples of data
effect
of various setups, preferred orientation etc.
|
IV.
Vibrational Spectroscopy
(IR,
NIR, Raman) in the Pharmaceutical Industry |
Chairperson:
Dr. Emil Cuirczak; Cadrai, Pharmaceutical Technology
Group, USA
1. Comparison of IR,
NIR, and Raman spectroscopy:
theory and practice.
2. Measurement techniques:
lab based (sampling) versus in situ measurements (inline,
PAT)
3. Physical Parameters that may be
measured:
a. Polymorphic Form and Ratios (macro and imaging)
b. Water of Hydration versus Surface Moisture
c. Particle Size
d. Crystallinity; Optical Isomers
4. Qualitative Analysis of Liquids
and Solids;
Rapid ID of Raw Materials and Actives
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Demonstration
Sessions
Tuesday
evening demonstration session.
Demonstration of Cambridge Structural Database search and analysis
Chairperson:
Dr. Sam Motherwell, ICDC, UK
Topics:
- substructure search
- molecular conformations
- H-bonds and other contacts
- statistics of geometric parameters
- probabilities of H-bonding motifs
- conformational assisted structure solution from XRPD
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