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IWPCPS®-1
IWPCPS®-2
IWPCPS®-3
IWPCPS®-4
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I W P C P S® 4 Preliminary Program
[ Fourth International Workshop on Physical Characterization of Pharmaceutical Solids ]
June 15 – 20, 2003, Stamford, CT USA
"Holiday Inn Select"

Tuesday, June 17, 2003
8:00 AM
Chair: G. Nichols, Pfizer Global Research & Development, UK
POLYMORPHS, SOLVATES AND SALTS
Hydrates and Solvates, Investigating the Suitability for Development Using Phase Diagrams and Analytical Tools
R. Storey; Pfizer Global R&D, UK
Optimisation of Solid State Properties by Salt Form/Polymorph Screening. A Case Study
P. Sieger; Boehringer Ingelheim, Germany
Rapid Salt Screening in Discovery Chemistry
H. Lieberman; Aventis, USA
Coffee Break
Determination of Polymorphs and/or Crystallinity of Drug Substances in Solid Pharmaceuticals by Spectroscopic Methods
K. Terada; Toho University, Japan
Solid State Analysis of the Dehydration of a Hydrate: A Case Study on Inosine
A. Gillon1, R. Davey1, N. Feeder2, R. Storey2; 1UMIST, UK; 2Pfizer Global R&D, UK
Towards a Fundamental Understanding of the Role of Nucleation in the Selection of Polymorphic Form: A Systematic Approach to Modeling Molecular Clusters up to the Critical Size
R. Hammond; University of Leeds, UK
Scale-up Effects in the Rates of Solution Mediated Polymorphic Transformations: The Role of Mass Transfer and Secondary Nucleation
E. Ferrari, R. Davey; UMIST, UK
DISCUSSION ROUND
Lunch
Tuesday, June 17, 2003 PM
SPECIAL XRD APPLICATIONS AND STRUCTURAL PROPERTIES
Role of X-ray Powder Diffraction and Complementary Techniques in Pharmaceutical Industry
M. Zakrzewski
Implications of Crystal Symmetry in the Engineering of Pharmaceutical Solids
S. Reutzel-Edens; Eli Lilly, USA
Combining Chemical Information from Solid-State NMR with Powder X-Ray Diffraction for the Crystal Structure Solution of “Challenging” Pharmaceutical Materials
R. Hammond1, C. Ma1, K.J. Roberts1, P.Y. Ghi2, R.K. Harris2; 1University of Leeds, UK; 2University of Durham, UK
Coffee Break
From Crystallization Process Development through Drug Substance and Drug Product Characterization: Applications of Polarized Light Microscopy and X-Ray Powder Diffraction
J. Smoliga; Boehringer Ingelheim, USA
H-bonding Motifs of Water with Chemical Groups in the Crystalline State
S. Motherwell; CCDC, UK
DISCUSSION ROUND
7:30 PM MIXER SPONSORED BY PANALYTICAL USA