| |
I
W P P C A S® 1
First International Workshop on the Pharmaceutical Physical Characterization of the Amorphous State
The IWPPCAS®-1 will be held May 8 - 9, 2006
The Amorphous State in Pharmaceuticals
Formulation of Amorphous Solids
Process Induced Disorder
Detection and Quantification of Low Levels of Amorphous Material
Stamford, CT
May 8 -9, 2006
Prof. Dr. Thomas Rhades, University of Otago, New Zealand
Prof. Dr. Marc Descamp, University of Lille, France
Dr. Angus Forster, GSK, UK
Dr. Angeline Zakrzewksi, assa, USA
Dr. Marek Zakrzewski, USA
The 2- day program is intended to benefit scientists and researchers in the areas of drug discovery, preformulation, formulation, stability testing, product development, product quality control, and analytical services.
Workshop participants will be exposed to several analytical approaches of pharmaceutical physical characterizing of the amorphous state.
This unique workshop will combine information about modern laboratory techniques to investigate the amorphous state in pharmaceutics and teaching about the amorphous state. It will offer fundamental approaches as well as up-to-date technical information and future outlooks.
The workshop is designed for scientists, formulators and regulatory personnel from the following areas:
Pharmaceutical Research and Development
- Ethical and Generic Pharmaceutical Production
- Excipient/Chemicals Production
- Veterinary Pharmaceutical Manufacturing
- Food Processing
- Compounding Pharmacists
- Regulatory Agencies
- Academia
- Analytical Equipment Manufacturers
- Analytical Laboratories
Please register early since the space is limited.
Oral presentations will last 25 minutes including 5 minutes discussion. At the end of each session will be a 30 minutes round table discussion.
Please submit by e-mail to Angeline@assainternational.com a maximum one page abstract in Word for Windows format until February 28, 2006.
May 8, 2006 AM
The Amorphous State in Pharmaceuticals
Chairperson: Prof. Dr. Thomas Rade; Otago University, New Zealand |
| Time |
Subject |
Author |
|---|
| 8:00-8:15 | Introduction | M. Zakrzewski,
assa international, USA |
| 8:15-9:15 | Fundamental Physics of the Amorphous State | M. Descamp, University of Lille; France |
| 9:15-10:15 | Quantification of the Degree Amorphous/ Crystallinity in Pharmaceuticals | T. Rades; Otago University, New Zealand |
| 10:15-10:45 | Coffee Break |
| 10:45-11:15 | TSC of Amorphous Systems | M. Antonijevic; University of East Anglia, Norwich, UK |
| 11:15-11:45 | Characterizing the Amorphous State in Differently Processed Pharmaceutical Powders | F. Thielmann, D. Burnett, Surface Measurement Systems, UK, and USA |
| 11:45-12:15 | Discussion Round |
| 12:15-1:30 | Lunch |
|
May 8, 2006 PM
Formulation of Amorphous Solids
Chairperson: Prof. Dr. Marc Descamp, University of Lille, France |
| Time |
Subject |
Author |
|---|
| 1:30-2:30 | A Practical Guide to Assess Suitability of Drug Polymer Mixtures for Formation of Glass Solutions | T. Rades;
Otago University, New Zealand |
| 2:30-3:30 | Amorphous Stabilisation | A. Forster;
PA Consulting, UK |
| 3:30-4:00 | Physical Stability of Amorphous Solid Dispersion: A Case Study on the Effect of Water | W. Xu and A. Sheth,
Merck & Co., Inc, USA |
| 4:00-4:30 | Coffee Break |
| 4:30-5:00 | Amorphous Phase: To Develop or Not? | S-D. Class,
MerckFrost; Canada |
| 5:00-5:30 | Discussion Round |
<
|
May 9, 2006 AM
Process Induced Disorder
Chairperson: Prof. Prof. Dr. Graham Buckton, University of London, UK |
| Time |
Subject |
Author |
|---|
| 8:00-9:00 | N.A. | G. Buckton,
University of London, UK |
| 9:00-9:30 | Solid State Transformations Induced by Milling and Dehydration | J.-F. Willart,
University of Lille, France |
| 9:30-10:00 | Amorphization as a Result of Processing, Effects on Chemical Stability | K. Jarring;
AstraZeneca, Sweden |
| 10:00-10:30 | Discussion Round |
| 10:30-11:00 | Coffee Break |
| 11:00-11:50 | Quantification of Low Levels of Crystalline Material in a Substantially Amorphous Matrix | R. Suryanarayanan,
University of Minnesota, USA |
| 11:50-12:20 | Quantification of low levels (1%) of Amorphous content in Carvedilol using Modulated DSC | M. V. Suryanarayana, V. Ranga Reddy, AnanthRaj Mohan,
Dr. Reddy's Laboratories Ltd., India
|
| 12:20-1:30 | Lunch |
|
May 9, 2006 PM
Detection and Quantification of Low Levels of Amorphous Material
Chairperson: Dr. Angus Forster; PA Consulting, UK |
| Time |
Subject |
Author |
|---|
| 1:30-2:00 | Quantitation and Characterization of Amorphous State By SWAXS | P. Laggner,
Austrian Academy of Science, Austria |
| 2:00-2:30 | Solid State NMR Characterization of Pharmaceutical Amorphous Materials | A. Medek;
Pfizer Inc, Connecticut, USA |
| 2:30-3:00 | Quantifying Low Levels of Amorphous Contents Using Vapor Sorption Techniques | F. Thielmann1, D. Burnett2,
1. Surface Measurement Systems UK, London, England
2. Surface Measurement Systems NA, Allentown, PA, USA |
| 3:00-3:30 | Discussion Round and Summary |
|
| Poster |
| - |
Subject |
Author |
|---|
| | Impact of Protein Concentration on the Glass Transition Behaviour of Bovine Serum Albumin (BSA) - Trehalose Formulations | F. Thielmann1, D Burnett2, and M. Naderi1
1. Surface Measurement Systems Ltd., London, UK
2. Surface Measurement Systems Ltd., Allentown, USA
|
| | Determination of Glass Transition Humidity by Dynamic Vapour Sorption | F. Thielmann1, D. Burnett2
1. Surface Measurement Systems Ltd., London, UK
2. Surface Measurement Systems Ltd., Allentown, USA
|
| | Investigating the kinetics of moisture-induced crystallization of amorphous lactose | F. Thielmann1, D. Burnett2
1. Surface Measurement Systems Ltd., London, UK
2. Surface Measurement Systems Ltd., Allentown, USA |
|
assa® reserves the right to change the faculty and agenda to accommodate situations beyond its control. ©2005 assa Inc.; all rights reserved.
Please
register as soon as possible with the online
registration form for the IWPPCAS-1, since space is limited.
We would like to encourage the participants to register before February 10.
Click here to get information about registration prices.
assa reserves the right to change the faculty and
agenda to accommodate situations beyond its control.
|
